The Ministry of Science & Technology on September 04, 2024, notified that the new heat-based approach to cancer treatment can reduce chemotherapy doses.
Researchers have used a combination of ultra-small magnetic nanoparticles (MDs) along with a heat shock protein 90 inhibitor (HSP90i) at suboptimal doses for effective magnetic hyperthermia-based cancer therapy. The technique could significantly enhance treatment efficacy by reducing the required chemotherapy dosage, serving as an adjuvant therapy that minimizes side effects.
The method published in ACS Nano is less invasive and causes fewer side effects. The research team demonstrated that MNPs, when exposed to an alternating magnetic field (AMF), can effectively combat tumors. This combined magnetic hyperthermia and chemotherapy (MHCT) approach can reduce the required amount of chemotherapy, making the treatment both safer and more effective. Additionally, the therapy can treat distant tumors without the need for an additional dose at the secondary tumor site, making it a highly effective cancer treatment.
Extensive global research is needed to realize the clinical application of the new therapy, potentially developing an adjuvant or alternative cancer therapy. The study paves the way for more efficient and tolerable anti-cancer treatments, offering substantial benefits to millions of patients and providing new directions for hyperthermia-based therapies.
[Release ID: 2051680]
